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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Microbes Infect. 2012 May 29;14(12):1054–1063. doi: 10.1016/j.micinf.2012.05.012

FIG. 4.

FIG. 4

Reduction of ehrlichial burden in C57BL/6-scid and C57BL/6 mice after treatment with a combination of anti-TRP sera compared to immune sera. Mice were infected intraperitoneally with 2×106 E. chaffeensis infected DH82 cells on day 0. SCID mice were administered a combination of anti-TRP32, anti-TRP47 and anti-TRP120 sera (TRPs), immune or control sera on days 7, 17, and mice were sacrificed 21 days post-infection. Immunocompetent C57BL/6 mice were administered a combination of anti-TRP32, anti-TRP47 and anti-TRP120 sera (TRPs), immune or control sera on day 3 and sacrificed 5 days post-infection. E. chaffeensis dsb copy number in the liver was determined by quantitative real-time PCR (A and C) and spleen weights (B and D) were compared to control mice. Three mice were used per group, and data are representative of one of three independent experiments. Graphs represent means ± SD, (*p<0.05, **p <0.005).