Figure 1.
Effect of anti-cancer agents on the production of VEGF and cell proliferation. (A) A549 cells were cultured in serum-starved medium with or without 10 μM cisplatin, 10 μM erlotinib, 1 μM paclitaxel or 1 μM gemcitabine for 24 h as indicated. VEGF protein levels were measured using an ELISA assay. Data are the mean of triplicate experiments, and bars represent the mean ± SD. *P<0.05. (B) A549 cells were cultured in serum-starved medium with or without 10 μM cisplatin, 10 μM erlotinib, 1 μM paclitaxel or 1 μM gemcitabine for 24 h as indicated. The effect of the agents on cell proliferation was examined using the MTT assay. Data are the mean of triplicate experiments, and bars represent the mean ± SD. *P<0.05.