Table IV.
Six highly significant (p<0.05) pathways in GHomas.
| Pathway ID | Pathway title | Gene | p-value |
|---|---|---|---|
| hsa04310 | Wnt signaling pathway | CCND3, LEF1, WNT5B, WNT5A, WIF1, FZD9, FZD2, FZD3, SFRP2, TBL1XR1, NFAT5, VANGL2, FRAT1, FZD7, PRICKLE1, SMAD3 | 0.004 |
| hsa04115 | p53 signaling pathway | TNFRSF10B, GADD45G, CCNE1, CCND3, CCNB2, PMAP1, IGFBP3, RPRM, CDKN1A (p21, CIP1) | 0.012 |
| hsa05217 | Basal cell carcinoma | LEF1, WNT5B, WNT5A, FZD9, FZD2, FZD3, FZD7 | 0.014 |
| hsa05218 | Melanoma | PIK3CD, FGF23, E2F3, PDGFRA, FGF17, PDGFC, FGF2, PIK3R3, CDKN1A | 0.016 |
| hsa05210 | Colorectal cancer | PIK3CD, LEF1, PDGFRA, FZD9, FZD2, FOS, FZD3, PIK3R3, FZD7 | 0.016 |
| hsa04512 | ECM-receptor interaction | LAMA2, ITGA2, COL11A1, COL6A1, COL6A2, COL4A6, SDC4, COL11A2 | 0.018 |