Table I.

Fold change in LAPC-4 xenograft tumors between control (PBS)- vs. oridonin- or RRE-treated animals.

Gene symbol	Gene name	Oridonin	RRE
ATF1	Activating transcription factor 1		2.9
BIRC2	Baculoviral IAP repeat-containing 2	2.1
NOD1	Nucleotide-binding oligomerization domain containing 1	2.3	2.3
CFLAR	CASP8 and FADD-like apoptosis regulator	1.6	1.8
EDARADD	EDAR-associated death domain	1.3	1.6
ELK1	ELK1, member of ETS oncogene family		1.7
FOS	V-fos FBJ murine osteosarcoma viral oncogene homolog		2.8
GJA1	Gap junction protein, α1, 43 kDa	1.6	1.4
HMOX1	Heme oxygenase (decycling) 1		1.8
HTR2B	5-Hydroxytryptamine (serotonin) receptor 2B	2.6	2.7
IFNG	Interferon-γ	−2.6
IKBKG	Inhibitor of κ light polypeptide gene enhancer in B-cells, kinase γ		1.6
IL1A	Interleukin 1α	2.2
IL1R1	Interleukin 1 receptor, type I	1.7	1.8
IL8	Interleukin 8		2.8
LTA	Lymphotoxin α (TNF superfamily, member 1)		1.9
MALT1	Mucosa associated lymphoid tissue lymphoma translocation gene 1	2.8	3.4
MAP3K1	Mitogen-activated protein kinase kinase kinase 1	2.7	2.6
PPM1A	Protein phosphatase 1A (formerly 2C), magnesium-dependent, α isoform	1.7	1.6
REL	V-rel reticuloendotheliosis viral oncogene homolog (avian)	2.7	2.6
TRIM13	Tripartite motif-containing 13	1.3	1.4
TICAM2	Toll-like receptor adaptor molecule 2	2.0	2.1
TLR3	Toll-like receptor 3	2.7	3.4