Table 1.
Profile of liver function test and ultrasound findings in different groups of Dengue infection
| Parameter | DF (n=59) | DHF (n=26) | DSS (n=25) | P value |
|---|---|---|---|---|
| Total serum bilirubin >2mg/dl | 0 (0%) | 1 (0.03%) | 2 (0.08%) | 0.025 |
| Mean total S. bilirubin (mg/dl) | 0.79 | 0.84 | 1.1 | 0.1 |
| Elevated ALT (U/l) | 41 (69.4%) | 22 (84.6%) | 23 (92%) | <0.001 |
| Mean ALT | 78.7 | 157.3 | 504.6 | 0.001 |
| Range | (16-374) | (25-481) | (24-3414) | |
| Elevated AST (U/l) | 52 (88.1%) | 26 (100%) | 24 (96%) | <0.001 |
| Mean AST | 134 | 280 | 883.4 | 0.002 |
| Range | (45-268) | (18-450) | (43-899) | |
| Elevated Alk Ph (U/l) | 27 (45.7%) | 17 (65.3%) | 18 (72%) | 0.049 |
| Mean AP | 118.6 | 157.7 | 188.2 | 0.03 |
| Range | (36-277) | (54-683) | (58-523) | |
| Mean serum albumin (gm/l) | 33.7 | 32.3 | 33.7 | 0.9 |
| Range | (28-42) | (25-42) | (26-40) | |
| Mean serum globulin(gm/l) | 19 | 28 | 28 | <0.001 |
| Range | (06-32) | (20-30) | (20-32) | |
| Mean total protein (gm/l) | 62 | 59 | 61 | 0.6 |
| Range | (55-79) | (50-70) | (50-73) | |
| Prolonged INR (>1.5) | 1 (1.6%) | 08 (30.7%) | 13 (52%) | 0.001 |
| Abnormal APTT (>3 sec above control) | 0 | 04 (15.3%) | 05 (20%) | 0.5 |
| Mean APTT in seconds | 31 | 34 | 33 | 0.3 |
| Ascites | 20 (33.9%) | 20 (76.9%) | 18 (72%) | <0.001 |
| Pleural effusion | 19 (32.2%) | 19 (73.1%) | 17 (68%) | <0.001 |
| Gall bladder thickening (>5mm) | 30 (50.8%) | 21 (80.8%) | 20 (80%) | 0.005 |
ALT: alanine transaminase; AST: aspartate transaminase; Alk. Ph: alkaline phosphatase; APTT: Activated partial thrombo-plastin time, INR: International Normalized Ratio