Table 2.
Distribution of pathogens of late-onset sepsis in 2004 and 2008
| Pathogen of sepsis | ||||
|---|---|---|---|---|
| Pathogen | 2004 | 2008 | P value | |
| Gram-positive microorganism | ||||
| Coagulase-negative Staphylococcus | 76 | 115 | 0.04 | |
| Staphylococcus aureus | 33 | 18 | NS | |
| Group B Streptococcus | 7 | 12 | NS | |
| Enterococcus spp. | 2 | 2 | NS | |
| Streptococcus spp. | 2 | 1 | NS | |
| Listeria monocytogenes | 1 | 1 | NS | |
| Subtotal | 121 (82.3%) | 149 (65.5%) | NS | |
| Gram-negative microorganism | ||||
| Escherichia coli | 7 | 18 | NS | |
| Klebsiella spp. | 10 | 29 | NS | |
| Enterobacter spp. | 1 | 1 | NS | |
| Serratia marcescens | 2 | 1 | NS | |
| Stenotrophomonas maltophilia | 0 | 6 | NS | |
| Pseudomonas aeruginosa | 1 | 14 | 0.01 | |
| Acinetobacter baumanii | 0 | 1 | NS | |
| Other | 1 | 0 | NS | |
| Subtotal | 22 (15%) | 70 (31%) | P<0.001 | |
| Candidaspp. | 4 (2.7%) | 8 (3.5%) | NS | |
| Total | 147 | 227 | P<0.001 | |
NS: Not significant