Table 4.
Planned Contrasts with Healthy Control Groupb | |||||||||||
Variable | Ultra High-Risk Subjectsa (N = 79) | First-Episode SchizophreniaSubjects (N = 30) | Healthy Control Subjects (N = 30) | Ultra High-Risk Group | First-Episode Schizophrenia Group | ||||||
Mean | SE | 95% CI | Mean | SE | 95% CI | Mean | SE | 95% CI | P | P | |
Facial affect recognition | |||||||||||
Sadness score | 63.7 | 0.03 | 57–70 | 63.8 | 0.05 | 54–73 | 82.2 | 0.06 | 70–94 | 0.017 | 0.028 |
Anger score | 68.1 | 0.03 | 62–74 | 52.4 | 0.05 | 43–62 | 61.7 | 0.06 | 50–73 | 0.386 | 0.248c |
Happiness score | 95.1 | 0.01 | 92–98 | 98.6 | 0.02 | 95–100 | 100.0 | 0.03 | 96–100 | 0.074 | 0.489 |
Disgust score | 63.5 | 0.04 | 56–71 | 62.5 | 0.06 | 51–74 | 69.2 | 0.07 | 55–83 | 0.523 | 0.488 |
Surprise score | 83.4 | 0.03 | 77–90 | 91.3 | 0.05 | 82–100 | 78.7 | 0.06 | 67–90 | 0.522 | 0.109 |
Fear score | 56.6 | 0.05 | 48–65 | 55.8 | 0.07 | 43–69 | 81.9 | 0.08 | 66–98 | 0.017 | 0.022 |
Neutral score | 86.2 | 0.02 | 81–91 | 91.5 | 0.04 | 85–99 | 91.7 | 0.05 | 83–100 | 0.328 | 0.976 |
Affective prosody recognition | |||||||||||
Sadness score | 51.0 | 0.03 | 45–57 | 50.4 | 0.04 | 42–59 | 60.8 | 0.06 | 50–72 | 0.158 | 0.163 |
Anger score | 90.8 | 0.01 | 88–94 | 89.6 | 0.02 | 86–94 | 97.7 | 0.03 | 93–100 | 0.037 | 0.024 |
Surprise score | 78.6 | 0.02 | 74–83 | 83.1 | 0.03 | 76–90 | 90.9 | 0.04 | 82–99 | 0.024 | 0.182c |
Fear score | 61.6 | 0.02 | 58–66 | 64.3 | 0.03 | 58–70 | 64.4 | 0.04 | 57–72 | 0.562 | 0.984 |
Neutral score | 72.1 | 0.02 | 68–77 | 73.8 | 0.03 | 67–81 | 77.7 | 0.04 | 69–86 | 0.298 | 0.504 |
Note:
Assessment of ultra high-risk subjects was based on state plus trait risk factors, attenuated symptoms, and/or brief limited intermittent psychotic symptoms.
P values of ANCOVA-derived planned contrasts adjusted for age, current IQ, and PANSS total symptom score with sex as additional factor.
The ANOVA-derived unadjusted P value was statistically significant.