Figure 1. Ketamine inhibition of GLIC at EC20.
(a) Representative current traces of GLIC expressed in Xenopus oocytes in the absence and presence of 100 µM ketamine. (b) Inhibition of the GLIC current by ketamine. Response to inhibition is expressed as a fraction of current induced at EC20 in the presence of an indicated concentration of ketamine relative to that in the absence of ketamine. The data are reported as the mean ± SEM from n ≥ 8 oocytes and fit to the Hill equation. Error bars less than the symbol size are not visible.