Figure 4.

Fission yeast origins are depleted of nucleosomes. (a) Average nucleosome occupancy for all replication peaks relative to the genome average is plotted log₂. (b) Average nucleosome occupancy of the NFRs nearest to each replication peak is plotted in red; the nucleosome occupancy of the NFRs nearest to an equal number of random non-origin locus is plotted in black. (c) Average nucleosome occupancy over all instances of each of the identified origin motifs relative to the genome average is plotted log₂. The logo for each motif is shown above.