Table 1.
Sense | Antisense | Percentage sense | Chi-square test P-value | |
---|---|---|---|---|
ERV TEV | 2,042 | 4,176 | 32.8% | 0.61 |
Apparently fixed ERV | 61,857 | 128,263 | 32.5% | |
LINE TEV | 3,803 | 5,336 | 41.6% | 3. 5 × 10-33 |
Apparently fixed LINE | 81,655 | 148,497 | 35.5% | |
SINE TEV | 4,192 | 5,528 | 43.1% | 1.2 × 0-4 |
Apparently fixed SINE | 282,011 | 343,528 | 45.1% |
For each TE superfamily the number of intronic variants within mouse genes with human orthologs was counted. B6+ TEVs and apparently fixed C57BL6/J TEs were counted as either sense or antisense with respect to the gene's transcriptional orientation. Significant differences between the orientation biases of apparently fixed and variant TEs were obtained using a chi-square test.