Table 3.
Five-year actuarial rates of local-regional control according to clinical and pathological disease status
| Factor | 5-year LRC rate | P-value |
|---|---|---|
| Clinical Stage | ||
| I/II (n = 475) | 95% | 0.05 |
| III (n = 120) | 90% | |
| Number positive nodes* | ||
| 0 to 3 (n = 517) | 95% | 0.03 |
| ≥ 4 (n = 75) | 87% | |
| pCR | ||
| No (n = 471) | 93% | 0.06 |
| Yes (n = 124) | 97% | |
| LVI | ||
| No (n = 500) | 95% | 0.02 |
| Yes (n = 95) | 89% | |
| Nuclear grade** | ||
| 1 or 2 (n = 198) | 97% | 0.03 |
| 3 (n = 396) | 92% | |
* In three patients the number of lymph nodes was unknown. ** In one patient, the nuclear grade was unknown. LRC, local-regional control; LVI, lymphovascular invasion; pCR, pathologic complete response