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Splicing isoforms generated by DNA variants of exons 19 and 20. A) Fluorescent RT-PCRs (blue peaks) of mutant minigenes were run in an ABI3130 DNA sequencer with Genescan ROX 500 (red peaks) as size standard. Chromatograms of different variants were overlaid to generate this picture. B) Diagrams of the splicing outcomes caused by variants of exons 19 and 20.
