Demonstration of invasive breast carcinomas with 18F-fluorodeoxyglucose (FDG) positron emission mammography (PEM). Images were made with dedicated breast PEM (Naviscan system; Naviscan, San Diego, CA, USA). PEM images show a 23-mm infiltrating ductal carcinoma in the right breast on medio-lateral oblique (MLO) view (a) and a left breast 12-mm infiltrating ductal carcinoma also on MLO view (b). Images are courtesy of James Rogers, of the Swedish Cancer Institute, and Lawrence MacDonald, of the University of Washington.