Table 3.

PTEN mutations in brain metastases

Sample	Mutations in gDNA				Mutations in cDNA	AI result	CGH (PTEN)
	Exon3	Exon4	Exon5	Exon6			result
BrM-6	Wt	g.del[72586_72627]	wt	nd	c.[del1241_1284]	AI	Het. loss
BrM-7	Wt	No product	wt	wt	Allele 1: c.[del1241_1665] Allele 2: [del1524_1665; dup1196_1240, 950_1240con1196_1523]	AI	Het. loss
BrM-8	wt	nd	c.389C > A	nd	nd	Normal	nd

het. Loss, heterozygous loss; nd, not determined; wt, wild type.