Table 1.
Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | |
---|---|---|---|---|---|---|---|
Type of SpA | AS | AS | AS | AS | AS | AS | AS |
Sacroiliitis | Grade 4 | Grade 4 | Grade 3 | Grade 4 | Grade 3 | Grade 3 | Grade 4 |
HLA-B27 | + | + | + | + | + | + | + |
Gender | Female | Female | Female | Male | Male | Female | Male |
Disease duration (years) | 9 | 27 | 11 | 6 | 4 | 24 | 19 |
Main location of inflammatory pain | Back, neck, chest, peripheral enthesitis (Achilles tendon, knee) | Neck, chest, peripheral enthesitisa | Back, buttock, chest | Neck | Back, neck, buttock | Back, neck, chest | Back, neck, peripheral enthesitis (Achilles tendon) |
Concomitant NSAIDs/steroids (dosage) | Yes/no | Yes/no | Yes/no | No/no | No/no | Yes/no | Yes/no |
Concomitant DMARDs | No | No | No | Sulfasalazine | No | No | No |
Previous biologics other than anti-TNF | Abatacept | Abatacept | Abatacept | No | No | No | No |
Patient 8 | Patient 9 | Patient 10 | Patient 11 | Patient 12 | Patient 13 | ||
Type of SpA | AS and PsA | uSpA | uSpA | uSpA | uSpA | uSpA | |
Sacroiliitis | Grade 3 | Grade 1 | Grade 0 | Grade 0 | Grade 0 | Grade 0 | |
HLA-B27 | - | + | + | + | + | + | |
Gender | Male | Female | Female | Male | Female | Male | |
Disease duration (years) | 15 | 11 | 9 | 25 | 6 | 12 | |
Main location of inflammatory pain | Back, neck, arthritis | Back, neck, buttock, chest | Back, buttock | Back, neck, buttock | Back, buttock, chest, peripheral enthesitis (Achilles tendon) | Back, neck | |
Concomitant NSAIDs/steroids (dosage) | No/no | Yes/no | Yes/no | No/no | Yes/no | No/yes (25 mg/day) | |
Concomitant DMARDs | No | No | No | No | No | No | |
Previous biologics other than anti-TNF | Rituximab | Abatacept | Abatacept | No | No | No |
AS, ankylosing spondylitis meeting modified New York criteria [33]; ASAS, Assessment of SpondyloArthritis International Society; DMARD, disease-modifying antirheumatic drug; NSAID, nonsteroidal anti-inflammatory drug; PsA, psoriatic arthritis meeting Classification Criteria for Psoriatic Arthritis [36]; SpA, spondyloarthritis; uSpA, undifferentiated spondyloarthritis. aLocation unknown.