Table 2.
Differences in serum uric acid levels according to quintiles of parathyroid hormone in NHANES 2003-2006
| Parathyroid hormone levels pM (pg/ml) |
Quintile 1 0.64-2.86 (6-27) |
Quintile 2 2.97-3.82 (28-36) |
Quintile 3 3.93-4.67 (37-44) |
Quintile 4 4.77-6.15 (45-58) |
Quintile 5 6.26-52.10 (59-491) |
P value for trend |
|---|---|---|---|---|---|---|
| Age- and sex-adjusted difference, μM mg/dl |
0 (referent) | 8.9 (3.3, 14.6) 0.15 (0.05, 0.25) |
15.2 (9.1, 21.3) 0.26 (0.15, 0.36) |
20.3 (14.0, 26.6) 0.34 (0.24, 0.45) |
35.9 (28.0, 43.8) 0.60 (0.47, 0.74) |
< 0.001 |
| Multivariate difference,a μM mg/dl |
0 (referent) | 7.6 (3.0, 12.2) 0.13 (0.05, 0.21) |
12.6 (6.7, 18.5) 0.21 (0.11, 0.31) |
14.2 (8.6, 19.8) 0.24 (0.14, 0.33) |
22.9 (16.3, 29.4) 0.39 (0.27, 0.49) |
< 0.001 |
| Multivariate difference,b μM mg/dl |
0 (referent) | 7.3 (2.9, 11.7) 0.12 (0.05, 0.20) |
13.2 (7.4, 19.0) 0.22 (0.12, 0.32) |
14.2 (8.9, 19.4) 0.24 (0.15, 0.33) |
18.0 (11.4, 24.6) 0.30 (0.19, 0.41) |
< 0.001 |
| Multivariate difference,c μM mg/dl |
0 (referent) | 7.5 (2.9, 12.2) 0.13 (0.05, 0.21) |
13.5 (7.2, 19.9) 0.23 (0.12, 0.34) |
14.4 (9.0, 19.8) 0.24 (0.15, 0.33) |
18.7 (11.8, 25.7) 0.31 (0.20, 0.43) |
< 0.001 |
aAdjusted for age, sex, race, body mass index, use of diuretics, allopurinol and uricosuric agents, and hypertension. bAdjusted for age, sex, race, body mass index, use of diuretics, allopurinol and uricosuric agents, hypertension, serum calcium levels, serum alkaline phosphatase levels, serum phosphorous levels, serum vitamin D levels, and glomerular filtration rate. cAdditionally adjusted for total daily intake of alcohol, energy, protein, sugar, and caffeine.