Table 4.
Associations between obesity measures and non-metabolic risk factors in African black and Caucasian women with RA
| Non-metabolic risk factor | Obesity measure | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BMI | Waist | Waist÷height | Log waist÷hip | |||||||||
| Black | Caucasian | Interaction | Black | Caucasian | Interaction | Black | Caucasian | Interaction | Black | Caucasian | Interaction | |
| P-value | P-value | P-value | P-value | |||||||||
| Age | -0.09 | -0.10 | 0.9 | -0.10 | -0.01 | 0.4 | -0.04 | 0.10 | 0.6 | -0.09 | 0.38b | 0.004 |
| Public healthcare | -0.05 | 0.07 | 0.4 | -0.08 | -0.01 | 0.3 | -0.04 | 0.13 | 0.4 | -0.07 | -0.04 | 0.5 |
| L py history smoking | -0.16 | 0.22a | 0.03 | -0.14 | 0.27a | 0.05 | -0.15 | 0.25a | 0.048 | 0.08 | 0.18 | 0.6 |
| Alcohol use | 0.07 | 0.05 | 0.08 | 0.06 | 0.07 | 0.04 | 0.03 | 0.06 | 0.08 | -0.08 | -0.02 | 0.5 |
| Exercise | -0.00 | -0.07 | 0.7 | 0.05 | -0.12 | 0.2 | 0.06 | -0.16 | 0.1 | -0.03 | -0.04 | 0.9 |
| DAS28 | -0.06 | 0.19 | 0.2 | 0.03 | 0.11 | 0.5 | 0.03 | 0.16 | 0.4 | -0.04 | 0.07 | 0.4 |
| L deformed joints | -0.25a | -0.15 | 0.2 | -0.32b | -0.06 | 0.01 | -0.28b | -0.08 | 0.036 | -0.11 | -0.10 | 0.2 |
| Prednisone use | -0.10 | -0.07 | 0.6 | -0.15 | 0.02 | 0.2 | -0.16 | -0.05 | 0.5 | -0.09 | 0.05 | 0.4 |
| Hypothyroidism | -0.11 | 0.16 | 0.1 | 0.04 | 0.08 | 0.9 | -0.04 | 0.11 | 0.4 | 0.05 | 0.03 | 0.7 |
| HRT | 0.04 | -0.06 | 0.6 | -0.02 | -0.07 | 0.8 | -0.04 | -0.07 | 0.9 | -0.09 | -0.04 | 0.5 |
| Anti-HTA use | 0.15 | 0.35b | 0.5 | 0.23a | 0.30† | 0.5 | 0.19 | 0.29b | 0.6 | 0.00 | 0.23a | 0.039 |
| Statin use | 0.10 | 0.30b | 0.4 | 0.10 | 0.29b | 0.8 | 0.05 | 0.28b | 0.2 | 0.06 | 0.06 | 0.8 |
| Ezetimibe use | ... | 0.17 | ... | ... | 0.08 | ... | ... | 0.11 | ... | ... | 0.02 | ... |
| OHA use | 0.27b | 0.25a | 0.5 | 0.31b | 0.25a | 0.5 | 0.29b | 0.26a | 0.7 | 0.00 | 0.14 | 0.3 |
| Insulin therapy | 0.25b | -0.05 | 0.06 | 0.26a | -0.03 | 0.07 | 0.30b | -0.05 | 0.042 | 0.09 | 0.03 | 0.6 |
Results are expressed as standardized regression coefficients in univariate analysis for the relationships between obesity measures and age and public healthcare and in age and public healthcare adjusted analysis for the associations between obesity measures and the other non-metabolic risk factor measures. Significant associations are shown in bold. aP-value < 0.05, bP-value < 0.01. BMI, body mass index; DAS28, Disease Activity Score in 28 joints; HRT, hormone replacement therapy; HTA, hypertensive agent; Log, logarithmically transformed; L, logarithmically transformed; OHA, oral hypoglycemic agent; py, pack year.