Table 3.
The meta- analysis result combined our data and Turkish data
| SNP | Nearest gene | Risk allele | Population | N | Risk allele frequency | P-value | Pc value | OR (95% CI) | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | |||||||
| rs11206377 | LOC100129342 | G | Turkisha | 152 | 170 | 66.1 | 51.4 | 3.0 × 10-4 | 1.5 × 10-3 | 1.8 (1.3 to 2.6) |
| (1p34) | Chinese | 147 | 951 | 56.5 | 53.9 | 0.410 | NS | 1.1 (0.9 to 1.4) | ||
| meta-analysis | 1.3 (1.1 to 1.6) | |||||||||
| rs2061634 | KIAA1529 | G | Turkish | 152 | 170 | 42.7 | 26.7 | 4.2 × 10-5 | 2.1 × 10-4 | 2.0 (1.5 to 2.9) |
| (9q22) | Chinese | 147 | 951 | 79.9 | 80.0 | 0.971 | NS | 1.0 (0.7 to 1.4) | ||
| meta-analysis | 1.4 (1.1 to 1.7) | |||||||||
| rs317711 | CPVL | C | Turkish | 152 | 170 | 25.5 | 13.2 | 1.0 × 10-4 | 5.0 × 10-4 | 2.2 (1.4 to 3.3) |
| (7p15-p14) | Chinese | 147 | 951 | 85.8 | 84.1 | 0.739 | NS | 1.3 (0.9 to 1.9) | ||
| meta-analysis | 1.6 (1.2 to 2.1) | |||||||||
| rs4936742 | UBASH3B | T | Turkish | 152 | 170 | 56.7 | 43.4 | 1.5 × 10-3 | 7.5 × 10-3 | 1.7 (1.2 to 2.4) |
| (11q24) | Chinese | 147 | 951 | 61.5 | 63.2 | 0.590 | NS | 0.9 (0.7 to 1.2) | ||
| meta-analysis | 1.2 (0.9 to 1.4) | |||||||||
| rs9513584 | UBAC2 | G | Turkish | 152 | 170 | 44.4 | 33.2 | 5.8 × 10-3 | 0.029 | 1.6 (1.2 to 2.3) |
| (13q32) | Chinese | 147 | 951 | 51.4 | 42.3 | 3.6 × 10-3 | 0.018 | 1.4 (1.1 to 1.8) | ||
| meta-analysis | 1.5(1.2 to 1.8) | |||||||||
aData from reference 19; OR (95% CI), Odds ratio (95%CI); NS: not significant; Pc: Bonferroni corrected P-value