Table 4.
Summary of the association of UBAC2 SNPs with Behcet's disease in Han Chinese population
| First-stage | Second-stage | Combined study | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SNPs | MA | AF | Pc Value | OR | 95% CI | AF | Pc | OR | 95% CI | AF | Pc | OR | 95% CI | |||
| Case | Ctrl | Case | Ctrl | Value | Case | Ctrl | Value | |||||||||
| rs3825427 | T | 116 (39.5) | 565 (29.7) | 2.2 × 10-3 | 1.5 | 1.2 to 2.0 | 248 (37.6) | 231 (30.4) | 9.3 × 10-3 | 1.4 | 1.1 to 1.7 | 364 (38.2) | 796 (29.8) | 6.9 × 10-6 | 1.5 | 1.2 to 1.7 |
| rs9517668 | T | 118 (41.5) | 573 (30.1) | 1.7 × 10-3 | 1.6 | 1.2 to 2.0 | 230 (34.8) | 219 (30.9) | 0.03 | 1.3 | 1.1 to 1.7 | 348 (36.5) | 792 (29.7) | 3.3 × 10-4 | 1.4 | 1.2 to 1.6 |
| rs9517701 | G | 117 (39.8) | 583 (30.7) | 5.1 × 10-3 | 1.5 | 1.2 to 1.9 | 249 (37.7) | 232 (30.3) | 9.0 × 10-3 | 1.4 | 1.1 to 1.7 | 366 (38.4) | 815 (30.5) | 2.9 × 10-5 | 1.4 | 1.2 to 1.7 |
95% CI, confidence interval; AF, allele frequency; MA, minor allele; OR, odds ratio; Pc: Bonferroni corrected P-value.