Table 1.
Clinical characteristics of patients with immunoglobulin G4-related disease (IgG4-RD).
| Case | Age | Serum IgG4 (mg/dL) |
RF | ANA | Clinical manifestation | Biopsy/IgG4/IgG ratio |
|---|---|---|---|---|---|---|
| 1 | 73 | 2890 | < 6 | 40 | Lymph, Mikulicz's disease Prostatitis |
Prostate/0.60 |
| 2 | 76 | 2210 | < 6 | 40 | Mikulicz's, RPF | Submandibular gland/0.40 |
| 3 | 79 | 1460 | < 6 | 160 (SS-A) |
IN, IP, Küttner's tumor, Lymph, RPF | Submandibular gland/0.73 |
| 4 | 66 | 1090 | 30.3 | 40 | AIP, IN, Renal pseudotumor | Kidney/0.70 |
| 5 | 73 | 592 | < 6 | 320 | IN, IP, Lymph, RPF, Sialadenitis | Submandibular gland/0.43 |
| 6 | 62 | 736 | 52.0 | < 40 | Sialadenitis, Lymph | Parotid gland/0.30* |
| 7 | 77 | 738 | < 6 | < 40 | Mikulicz's disease | ND. |
| 8 | 74 | 389 | < 6 | < 40 | Retro-orbital tumor | Retro-orbital tumor/0.48 |
| 9 | 76 | 760 | < 6 | 40 | AIP, Periureteritis | Ureter/0.38 |
| 10 | 52 | 383 | < 6 | < 40 | Küttner's tumor | Submandibular gland/0.57 |
| 11 | 70 | 724 | < 6 | < 40 | Küttner's tumor, Lymph | Submandibular gland/0.40 |
| 12 | 46 | 675 | 26.8 | 80 | Mikulicz's disease | Lachrymal gland/0.41 |
| 13 | 37 | 533 | < 6 | < 40 | Mikulicz's disease | Lachrymal gland/0.50 |
| 14 | 77 | 655 | < 6 | 80 | RPF | ND |
| 15 | 76 | 458 | < 6 | < 40 | AIP, RPF | Retroperitoneal/0.70 |
| 16 | 62 | 315 | < 6 | 40 (SS-A) |
AIP, RPF | Pancreas/0.43 |
| 17 | 79 | 309 | ND | < 40 | RPF | ND |
| 18 | 79 | 1960 | 65 | 40 | Orbital tumor, Lymph, Lung nodule | Orbital tumor/0.59 |
AIP, autoimmune pancreatitis; ANA, antinuclear antibody; IN, interstitial nephritis; IP, interstitial pneumonia; Lymph, lymphadenopathy; ND, not determined; RF, rheumatoid factor; RPF, retroperitoneal fibrosis; SS-A, anti-SS-A antibody; *, IgG4-positive plasmacytes > 100/high-power fields.