Table 2.
RT-PCR of 21 cytokine genes expressed as Delta Ct value and stratified by LN
| n (%) of positive patients | All n = 46 | LN+ n = 20 (43.5%) | LN- n = 26 (52.4%) | Wilcoxon P value | |
|---|---|---|---|---|---|
| CCR7 | 45 (98%) | 8 (-10; -7) | -8 (-9; -7) | -8 (-10; -7) | 0.465 |
| IFN-γ | 35 (76%) | -10 (-12; -9) | -10 (-11; -9) | -11 (-12; -8) | 0.656 |
| IL-10 | 45 (98%) | -7 (-8; -6) | -7 (-8; -7) | -7 (-8; -6) | 0.312 |
| IL-12A | 41 (89%) | -9 (-10; -8) | -9 (-10; -8) | -10 (-11; -8) | 0.188 |
| IL-13 | 11 (24%) | -14 (-15; -13) | -15 (-16; -15) | -13 (-14; -11) | 0.109 |
| IL-15 | 42 (91%) | -9 (-9; -8) | -8 (-9; -8) | -9 (-10; -8) | 0.104 |
| IL-17A | 15 (33%) | -11 (-13; -9) | -13 (-14; -11) | -11 (-11; -9) | 0.121 |
| IL-18 | 46 (100%) | -6 (-7; -6) | -7 (-7; -6) | -6 (-7; -5) | 0.418 |
| IL-1β | 43 (94%) | -8 (-9; -7) | -9 (-9; -8) | -8 (-9; -7) | 0.517 |
| IL-2 | 29 (59%) | -12 (-14; -11) | -13 (-14; -11) | -12 (-14; -12) | 0.846 |
| IL-21 | 20 (43%) | -13 (-14; -12) | -13 (-14; -12) | -13 (-14; -12) | 0.909 |
| IL-22 | 7 (15%) | -12 (-14; -11) | -13 (-15; -12) | -11 (-13; -11) | 0.629 |
| IL-23A | 45 (98%) | -5 (-6; -5) | -5 (-6; -4) | -6 (-8; -5) | 0.058 |
| IL-28A | 21 (46%) | -10 (-12; -9) | -10 (-12; -8) | -11 (-11; -10) | 0.622 |
| IL-33 | 41 (89%) | -11 (-12; -9) | -11 (-12; -9) | -11 (-12; -9) | 0.646 |
| IL-6 | 44 (96%) | -8 (-10; -6) | -8 (-9; -7) | -8 (-10; -5) | 0.706 |
| IL-7 | 44 (96%) | -6 (-7; -6) | -6 (-7; -5) | -7 (-7; -6) | 0.608 |
| IL-8 | 46 (100%) | -4 (-6; -2) | -4 (-5; -3) | -3 (-6; -2) | 0.877 |
| LTβ | 44 (96%) | -6 (-8; -5) | -6 (-7; -5) | -6 (-8; -6) | 0.443 |
| TGF-β1 | 46 (100%) | -3 (-4; -2) | -3 (-4; -3) | -3 (-3; -2) | 0.050 |
| TNF-α | 46 (100%) | -7 (-8; -6) | -7 (-8; -6) | -7 (-8; -6) | 0.816 |