Table 1.
Characteristics of patients with idiopathic inflammatory myopathies and healthy controls
| Characteristic | IIM | HC |
|---|---|---|
| N | 42 | 27 |
| Age (years) | 53.8 ± 14.2 | 49.5 ± 8.6 |
| Sex (F/M) | 31/11 | 22/5 |
| CRP (mg/l) | 9.3 ± 21.6 | 1.8 ± 1.5 |
| CK (ukat/l, ULN 2.7) | 33.6 ± 58.2 | NA |
| Myoglobin (μg/l, ULN 70) | 1345 ± 2422 | NA |
| Clinical activity of myositis | ||
| MYOACT global | 0.15 ± 0.11 | NA |
| MMT8 (maximum 80) | 65.34 ± 12.31 | NA |
| Autoantibodies (%) | ||
| Anti-Jo-1 | 24 | NA |
| Anti-Ro-52 | 37 | NA |
| Anti-Ro-60 | 2 | NA |
| Anti-PL-7 | 5 | NA |
| Anti-PM-Scl-100 | 12 | NA |
| Anti-PM-Scl-75 | 7 | NA |
| Anti-Mi-2 | 12 | NA |
| Anti-Ku | 2 | NA |
| Anti-SRP | 5 | NA |
| Anti-U1RNP | 5 | NA |
| Anti-histones | 5 | NA |
| Other (AMA, M2, CENP-B) | 2 | NA |
| Negative | 21 | NA |
| Treatment (%) | ||
| Before therapy | 19 | 0 |
| Treatment less than 1 month | 53 | 0 |
| Treatment more than 1 month | 26 | 0 |
| Glucocorticoids | 67 | 0 |
| Others | 19 | 0 |
Abbreviations: CK, creatine kinase; CRP, C-reactive protein; F, female; HC, healthy controls; IIM, inflammatory myopathies; M, male; MMT8, manual muscle testing of eight muscle groups; MYOACT, disease activity assessment visual analogue scales; N, number; NA, not analysed