Table 3.
Linear regression analysis for general and RA disease-related characteristics and endothelial function in RA patients from the cross-sectional study
| Microvascular function | Macrovascular function | |||
|---|---|---|---|---|
| Endothelium-dependent | Endothelium- independent | Endothelium- dependent | Endothelium- independent | |
| RA disease-related characteristics | ||||
| Disease duration | β = -0.12, P = 0.29 | β = 0.21, P = 0.07 | β = -0.04 P = 0.76 | β = -0.12, P = 0.34 |
| LogCRP | β = -0.61, P = 0.05 | β = 0.10, P = 0.32 | β = 0.15, P = 0.13 | β = 0.00, P = 0.97 |
| LogESR | β = -0.09, P = 0.41 | β = 0.18, P = 0.10 | β = -0.01, P = 0.95 | β = -0.08, P = 0.46 |
| DAS28 | β = 0.15, P = 0.15 | β = 0.02, P = 0.84 | β = 0.06, P = 0.59 | β = -0.01, P = 0.93 |
| General characteristics | ||||
| Age | β = -0.37, R2 = 0.135c | β = -0.20, R2 = 0.042a | β = -0.24, R2 = 0.55a | β = -0.36, R2 = 0.126c |
| BMI | β = 0.21, P = 0.05 | β = 0.08, P = 0.41 | β = -0.12, P = 0.26 | β = -0.21, P = 0.05 |
| Resting SBP | β = -0.11, P = 0.30 | β = -0.02, P = 0.88 | β = -0.11, P = 0.27 | β = -0.27, R2 = 0.066b |
| Resting DBP | β = 0.04, P = 0.67 | β = 0.08, P = 0.44 | β = -0.12, P = 0.25 | β = -0.05, P = 0.61 |
RA disease-related characteristics and general characteristics were entered as independent variables, whereas microvascular and macrovascular endothelial functions were entered as dependent variables in the regression analysis. BMI, body mass index; CRP, C-reactive protein; DAS28, disease activity score in 28 joints; DBP, diastolic blood pressure; ESR, erythrocyte sedimentation rate; SBP, systolic blood pressure. aP < 0.05; bP < 0.01; cP < 0.001. R2 value is shown for all significant associations only.