Table 6.
Endothelial function during treatment in the longitudinal study
| Baseline | 2 weeks | 12 weeks | Treatment effect | Degrees of freedom | |
|---|---|---|---|---|---|
| Microvascular function | |||||
| Endothelium-dependent (Ach%) | 314 ± 214 | 423 ± 250a | 348 ± 209b | F = 5.09, P = 0.01 | 2, 21 |
| Endothelium-independent (SNP%) | 247 ± 126 | 284 ± 147 | 261 ± 152 | F = 1.18, P = 0.32 | 2, 21 |
| Macrovascular function | |||||
| Endothelium-dependent (FMD%) | 9.4 ± 6.8 | 12.0 ± 10.0 | 12.0 ± 8.1 | F = 1.60, P = 0.21 | 2, 19 |
| Endothelium-independent (GTN%) | 22 ± 7.4 | 23 ± 7.2 | 24 ± 7.2 | F = 0.31, P = 0.74 | 2, 19 |
Results are expressed as mean ± standard deviation. aDifferent from baseline. bDifferent from 2 weeks. Ach, acetylcholine; FMD, flow-mediated dilatation; GTN, glyceryl trinitrate-mediated dilatation; SNP, sodium nitroprusside.