Table 7.
Levels of individual biomarkers comprising principal component 3 stratified by smoking status
| Smoking status | ||||||
|---|---|---|---|---|---|---|
| Variable (pg/ml) | Never (n = 61) | Past (n = 56) | Current (n = 40) | P valuea | Ever (n = 96) | P valueb |
| MMP-8 | 9,750 (4,767 to 14,668) | 12,578 (6,906 to 26,066) | 18,934 (10,792 to 28,988) | 0.02 | 16,731 (8,001 to 27,241) | 0.004 |
| MMP-9 | 377,000 (258,488 to 607,190) | 421,409 (248,758 to 627,056) | 547,697 (344,692 to 802566) | 0.01 | 466,416 (284,003 to 730,264) | 0.04 |
| CXCL8 | 27.0 (21.1 to 40.5) | 30.0 (23.2 to 53.0) | 34.0 (20.1 to 88.9) | 0.4 | 31.9 (21.3 to 52.2) | 0.2 |
| HGF | 421.7 (327.8 to 678.3) | 430.3 (305.9 to 648.3) | 408.4 (337.7 to 555.2) | 1.0 | 427.1 (327.8 to 646.1) | 0.9 |
HGF, hepatocyte growth factor; MMP, matrix metalloproteinase. aKruskal-Wallis test. bEver smoked versus never smoked (Mann-Whitney U test).