Table 1.
control rats (n = 8) |
AIA rats (n = 20) |
nor-NOHA treated rats (n = 20) |
|
---|---|---|---|
Body weight (g) | 310 ± 3 | 279 ± 10* | 269 ± 5* |
Arthritis score | 0 | 1.3 ± 0.2* | 1.1 ± 0.2* |
Ankle diameter (mm) | 7.6 ± 0.1 | 8.3 ± 0.2* | 8.3 ± 0.1* |
Histological score | 0 | 4.1 ± | 3.7 ± 1* |
Radiological score | 0 | 2.2 ± | 2.1 ± 0.6* |
IL-6 (pg/ml) | 366 ± 22 | 419 ± 17* | 378 ± 22 |
VEGF (pg/ml) | 488 ± 36 | 642 ± 34* | 500 ± 65 |
Data were obtained 21 days after the onset of arthritis in control rats, AIA rats and nor-NOHA treated rats. Values are the mean ± SEM. * = P <0.05 vs control