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. 2012 Jun 4;14(3):R133. doi: 10.1186/ar3866

Figure 1.

Figure 1

Representative immunohistochemical findings of synovial TRAF6 expression. A, Mild synovial TRAF6 expression in an OA patient; B, Intensive synovial TRAF6 expression in a RA patient; C, Expression of TRAF6 in intimal layer of the synovium in a RA patient. The arrows point to TRAF6+ synoviocytes located at intimal layer of the synovium; D, Expression of TRAF6 in subintimal layer of the synovium in a RA patient. The arrows point to TRAF6+ plasmocytes located at the subintimal layer of the synovium. (Anti-TRAF6 immunostaining, original magnification: A and B ×100, C and D ×400. OA, osteoarthritis; RA, rheumatoid arthritis; TRAF6, Tumor necrosis factor receptor-associated factor 6).