Table 2.
IFN-γ levels in the tuberculosis antigen-stimulated wells and mitogen-stimulated wells that were used as positive controls
| RA-TNF1 (n = 38) | RA-TNF2 (n = 38) | TNF-naive RA (n = 40) |
TB (n = 30) |
Leprosy (n = 23) |
Healthy controls (n = 41) | |
|---|---|---|---|---|---|---|
| IFN-γ level in tuberulosis antigen well (IU/ml) | 3.6 ± 8.4 | 3.0 ± 6.2 | 2.8 ± 5 | 2.3 ± 4.2 | 7.3 ± 8.0 | 3.5 ± 6.4 |
| IFN-γ level in positive control well (IU/ml) | 7.0 ± 6.4 | 16.1 ± 14.2a | 8.7 ± 6.1 | 11.6 ± 12.1 | 12.2 ± 6.1 | 17.3 ± 6.4 |
aThe mitogen-nil level increased significantly (P < 0.001) after treatment with TNF-α antagonists.