Table 3.
QPCR of chondrogenic and fibrogenic gene expression in meniscus/synovium
| acan | Fold2 | col2a | Fold2 | col10a | Fold2 | col1a | Fold2 | col3a | Fold2 | col5a | Fold2 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ΔCT1 | ΔCT1 | ΔCT1 | ΔCT1 | ΔCT1 | ΔCT1 | |||||||
| Naive | 3.28 | 1.00 | 3.73 | 1.00 | 5.50 | 1.00 | -0.21 | 1.00 | 0.05 | 1.00 | 3.46 | 1.00 |
| Acute | -0.89 | 17.5 | -1.59 | 39.9 | 1.92 | 11.9 | -6.89 | 102 | -0.13 | 1.13 | 1.43 | 4.08 |
| TTR | 0.79 | 5.61 | -1.41 | 35.3 | 1.35 | 17.7 | -4.90 | 25.8 | -3.66 | 13.1 | -1.40 | 29.0 |
| TTR+HA | 2.99 | 1.22 | 2.63 | 2.10 | 4.76 | 1.67 | -1.45 | 2.43 | -1.11 | 2.23 | 2.12 | 2.53 |
| TTR+SA | 1.10 | 4.53 | -1.25 | 31.5 | 1.46 | 16.4 | -6.10 | 59.3 | -2.68 | 6.63 | -0.98 | 21.7 |
1relative to GAPDH, mean (SD) ΔCT of 2 pools with 8 mice per pool for Naïve and 2 pools with 12 mice per pool for all 4 treatment groups. Values represent the average of the two pools, with the difference between duplicates being < 20% of average pool value.
2Fold Changes are relative to Naive