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Relationships between CMV-specific and HSV-2-specific CD4 T cells in coinfected persons. P values for Pearson correlations are indicated. (A) Proportions of circulating CD4 T cells responsive with HSV-2 (x axis) and CMV (y axis) in 46 coinfected persons. (B) The proportions of CMV-specific CD4 T cells that express two or three cytokines are indicated on the y axis. The x axis shows the proportion of HSV-2-specific CD4 T cells with polyfunctionality.
