Fig 1.
(A) Summary of number and timing of isolation of envelope clones for mother-infant pairs. aTime since delivery. N/A, not applicable. (B) Neighbor-joining tree based on pairwise distance of full-length envelope sequences from S208 and F535 maternal (sequence names begin with “M”) and infant (sequence names begin with “B”) variants. Bootstrap values are indicated to the left of nodes. Maternal and infant variants analyzed for detailed epitope mapping are highlighted in black and gray boxes, respectively. IC50s are indicated in parentheses to the right of sequence names. Pairwise distances in the envelopes of all maternal and baby variants compared to baby variants from the same mother-infant pair analyzed in this study are indicated next to the IC50s.