Fig 7.

Rate of in vitro neutralization of CD46- and CD55-containing MuV and VSV. One hundred PFU of MuV (A) or VSV (B) derived from the indicated cell lines was incubated with NHS from two different donors for the indicated times, and then remaining infectivity was determined by plaque assay. As a control, virus was incubated with PBS alone for 1 h. Data are from six independent reactions, and error bars represent standard deviations. ^, P < 0.0001 when comparing virus with CD46 only to virus from control CHO-K1 cells; *, P < 0.0001 when comparing virus containing CD55 only to virus containing CD46 only.