Figure 3.

Reference cross-angle (Ω) distribution. (Dashed line) Reference cross-angle distribution of two helices with fixed tilt angles, ${\theta }_1^{\prime }$ and ${\theta }_2^{\prime }$, and random projection angle, γ; (solid line) reference cross-angle distribution of two helices with normally distributed tilt angles with mean ${\theta }_1^{\prime }$, ${\theta }_2^{\prime }$ and standard deviation σ₁, σ₂, respectively. These mean and standard deviation values correspond to the experimental tilt angles at hydrophobic mismatch ranges Δd₁ = 30 Å and Δd₂ = 10.0 Å, respectively, as extracted from Fig. 2a. These amount to ${\theta }_1^{\prime }$ = 23.6°, ${\theta }_2^{\prime }$ = 29.4°, σ₁ = 11.3°, and σ₂ = 12. 4°. A schematic sketch of helices is provided for both extremes of γ = 0° and γ = 180°.