Skip to main content
. 2010 Sep 29;1(6):1035–1040. doi: 10.3892/etm.2010.154

Table II.

Associations between rs11614913, rs2910164 and rs3746444 SNPs and clinicopathological subtypes of GC.

Variables (n) rs11614913 genotype
rs2910164 genotype
rs3746444 genotype
TT TC CC CC CG GG AA AG GG
Overall GC (127) 36 63 28 64 49 14 82 33 12
Lauren's classification (127)
  Diffuse type (54) 16 27 11 25 25 4 37 12 5
  Intestinal type (73) 20 36 17 39 24 10 45 21 7
Staging (127)
  Early (57) 19 27 11 28 20 9 36 16 5
  Advanced (70) 17 36 17 36 29 5 46 17 7
Lymphatic invasion (98)
  Negative (37) 9 18 10 17 13 7 22 11 4
  Positive (61) 19 32 10 31 25 5 39 17 5
Venous invasion (98)
  Negative (65) 20 32 13 31 24 10 42 17 6
  Positive (33) 8 18 7 17 14 2 19 11 3
Lymph node metastasis (127)
  Negative (65) 18 34 13 32 24 9 42 17 6
  Positive (62) 18 29 15 32 25 5 40 16 6
Peritoneal dissemination (127)
  Negative (101) 31 49 21 48 41 12 64 28 9
  Positive (26) 5 14 7 16 8 2 18 5 3
Liver or distant metastasis (127)
  Negative (120) 35 60 25 59 48 13 76 32 12
  Positive (7) 1 3 3 5 1 1 6 1 0
Morphology (early GC) (57)
  Polypoid or elevated type (23) 7 9 7 12 8 3 14 6 3
  Depressed type (34) 12 18 4 16 12 6 22 10 2
Morphology (advanced GC) (70)
  Borrmann type I (4) 1 2 1 2 2 0 3 0 1
  Borrmann type II (24) 6 13 5 12 10 2 14 8 2
  Borrmann type III (34) 9 17 8 18 14 2 22 8 4
  Borrmann type IV (8) 1 4 3 4 3 1 7 1 0

rs11614913 CC vs. TT+TC: depressed type vs. polypoid or elevated type; age- and gender-adjusted OR=6.29, 95% CI 1.18–33.47, p=0.03.