Table II.
Variables (n) | rs11614913 genotype
|
rs2910164 genotype
|
rs3746444 genotype
|
||||||
---|---|---|---|---|---|---|---|---|---|
TT | TC | CC | CC | CG | GG | AA | AG | GG | |
Overall GC (127) | 36 | 63 | 28 | 64 | 49 | 14 | 82 | 33 | 12 |
Lauren's classification (127) | |||||||||
Diffuse type (54) | 16 | 27 | 11 | 25 | 25 | 4 | 37 | 12 | 5 |
Intestinal type (73) | 20 | 36 | 17 | 39 | 24 | 10 | 45 | 21 | 7 |
Staging (127) | |||||||||
Early (57) | 19 | 27 | 11 | 28 | 20 | 9 | 36 | 16 | 5 |
Advanced (70) | 17 | 36 | 17 | 36 | 29 | 5 | 46 | 17 | 7 |
Lymphatic invasion (98) | |||||||||
Negative (37) | 9 | 18 | 10 | 17 | 13 | 7 | 22 | 11 | 4 |
Positive (61) | 19 | 32 | 10 | 31 | 25 | 5 | 39 | 17 | 5 |
Venous invasion (98) | |||||||||
Negative (65) | 20 | 32 | 13 | 31 | 24 | 10 | 42 | 17 | 6 |
Positive (33) | 8 | 18 | 7 | 17 | 14 | 2 | 19 | 11 | 3 |
Lymph node metastasis (127) | |||||||||
Negative (65) | 18 | 34 | 13 | 32 | 24 | 9 | 42 | 17 | 6 |
Positive (62) | 18 | 29 | 15 | 32 | 25 | 5 | 40 | 16 | 6 |
Peritoneal dissemination (127) | |||||||||
Negative (101) | 31 | 49 | 21 | 48 | 41 | 12 | 64 | 28 | 9 |
Positive (26) | 5 | 14 | 7 | 16 | 8 | 2 | 18 | 5 | 3 |
Liver or distant metastasis (127) | |||||||||
Negative (120) | 35 | 60 | 25 | 59 | 48 | 13 | 76 | 32 | 12 |
Positive (7) | 1 | 3 | 3 | 5 | 1 | 1 | 6 | 1 | 0 |
Morphology (early GC) (57) | |||||||||
Polypoid or elevated type (23) | 7 | 9 | 7 | 12 | 8 | 3 | 14 | 6 | 3 |
Depressed type (34) | 12 | 18 | 4 | 16 | 12 | 6 | 22 | 10 | 2 |
Morphology (advanced GC) (70) | |||||||||
Borrmann type I (4) | 1 | 2 | 1 | 2 | 2 | 0 | 3 | 0 | 1 |
Borrmann type II (24) | 6 | 13 | 5 | 12 | 10 | 2 | 14 | 8 | 2 |
Borrmann type III (34) | 9 | 17 | 8 | 18 | 14 | 2 | 22 | 8 | 4 |
Borrmann type IV (8) | 1 | 4 | 3 | 4 | 3 | 1 | 7 | 1 | 0 |
rs11614913 CC vs. TT+TC: depressed type vs. polypoid or elevated type; age- and gender-adjusted OR=6.29, 95% CI 1.18–33.47, p=0.03.