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. Author manuscript; available in PMC: 2012 Sep 19.
Published in final edited form as: Adv Enzyme Regul. 2007 Mar 6;47:271–280. doi: 10.1016/j.advenzreg.2006.12.011

Scheme 2.

Scheme 2

Schematic of the effect of protean agonism of the S1P1 receptor with SB649146 and the consequential effect on the engagement of S1P1 receptor with the PDGFβ receptor signaling system.