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. Author manuscript; available in PMC: 2012 Sep 19.
Published in final edited form as: Drug Dev Res. 2004 Oct 5;28(3):226–231. doi: 10.1002/ddr.430280307

Figure 2.

Figure 2

A proposed model for canine A2a receptors deduced from the primary sequence, including seven transmembrane helices (I–VII), three extracellular loops (E-I–III), two histidinyl residues possibly involved in ligand binding (H), a sodium binding site (Na), and hypothetical disulfide bonds (S-S, residue numbers in italics) and thiol groups. Thiol of Cys82 is not shown.