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. Author manuscript; available in PMC: 2013 Sep 13.
Published in final edited form as: J Med Chem. 2012 Aug 21;55(17):7425–7436. doi: 10.1021/jm300351w

Figure 5.

Figure 5

Binding site of 2 bound to PfDHODH. A limited set of residues within the 4Å shell of the bound inhibitor are displayed. 2 and orotate are displayed in pink and FMN is displayed in yellow. Hydrogen bonding distances are displayed in Å. The structure (3I6R.pdb) is displayed in PyMol.