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. Author manuscript; available in PMC: 2013 Apr 5.
Published in final edited form as: Neuroscience. 2012 Jan 12;207:307–315. doi: 10.1016/j.neuroscience.2012.01.008

Figure 3. mRNA expression of CBRs and chemokine receptors and protein expression of Iba1 24 hours after neonatal MCAO.

Figure 3

MCAO in P7 rats induced the expression of CB2R (A), but not of CB1R (B) 24 hours after neonatal stroke. Expression of CBRs was unaffected by WIN (A and B, n=5–7). WIN led to a decreased protein expression of Iba1 in the injured brain at 24 hours (C). MCAO in P7 rats induced the expression of CCR2 and CX3CR1, that was unaffected by WIN (D and E, n=5–7). Data are expressed as fold increase expression vs the corresponding naives (Veh or WIN) or the contralateral hemisphere; (*) Student’s t-test p<0.05 vs contralateral MCAO+Veh; (#, ##, ###) Student’s t-test p<0.05, p<0.01, p<0.001, respectively, vs contralateral MCAO+WIN.