Table 1. Biochemical markers (mean ± SD) of vitamin D status, bone turnover and metabolism in patients and controls.
| Patients (n = 99) | Controls (n = 159) | 95% CI | p value | |
| 25(OH)D (nmol/l) | 68.4±24.5 | 68.5±22.9 | −6.0, 5.9 | 0.992 |
| 1,25(OH)2D (pmol/l) | 119.9±43.7 | 127.0±44.9 | −18.4, 4.1 | 0.211 |
| PTH (pmol/l) | 3.55±1.89 | 3.68±1.83 | −0.60, 0.34 | 0.585 |
| Ionized calcium (mmol/l) | 1.27±0.03 | 1.27±0.04 | −0.01, 0.01 | 0.986 |
| Phosphate (mmol/l) | 1.14±0.15 | 1.09±0.16 | 0.01, 0.09 | 0.012 |
| DBP (µmol/l) | 4.28±0.72 | 4.18±0.73 | −0.08, 0.29 | 0.255 |
| Creatinine (µmol/l) | 66.2±11.1 | 69.0±11.8 | −5.7, 0.1 | 0.060 |
| bALP (Ua/l) | 24.2±7.6 | 22.6±7.2 | −0.2, 3.5 | 0.081 |
| NTX (nmol/l BCEb/mmol/l Crc) | 54.7±42.2 | 44.6±23.0 | 2.1, 18.2 | 0.030 |
25(OH)D: 25-hydroxyvitamin D, 1,25(OH)2D: 1,25-dihydroxyvitamin D, PTH: parathyroid hormone, DBP: vitamin D binding protein, bALP: bone alkaline phosphatase, NTX: cross-linked N-terminal telopeptide of type 1 collagen (all measured in serum, except NTX that was measured in urine).
a
Enzyme activity measured in U/l, 1U: one unit of bALP activity was defined as 1 µmol of p-nitrophenyl phosphate hydrolyzed per minute at 25°C,
b
BCE: Bone Collagen Equivalents,
c
Cr: Creatinine. Comparison of groups was calculated using independent two-tailed t test. CI: mean difference confidence interval.