Figure 2. Relative and absolute loss of CCR7⁺CD56^bright NK cells is not attributable to apoptosis.

(A) Absolute cell numbers of CD56^bright NK cells are depicted. Horizontal bars indicate means. (B) Absolute cell numbers of either CCR7⁺ or CCR7⁻CD56^bright NK cells are shown. (C) Representative flow cytometry data of CD95 on gated CD56^bright NK cells and respective summary data derived from untreated HIV-patients. Numbers in flow cytometry plots indicate frequencies of quadrants and horizontal bars in dot plot indicate mean values. (D) Pearson’s correlation analysis between frequencies of CCR7- and CD69-expressing CD56^bright NK cells. *, P<0.05; ***, P<0.001; NS – not significant.