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Average sizes and zeta potentials of NPs.
| Particle | Size (nm) | Surface charge (mV) |
|---|---|---|
| PLGA NPs | 170 ± 6.1 | −16 ± 3.5 |
| PLGA-TAT NPs | 225 ± 33 | −9.8 ± 2.8 |
| PTX/PLGA NPs | 297 ± 55 | −9.3 ± 4 |
| PTX/PLGA-TAT NPs | 250 ± 35 | −15 ± 4.3 |
Data represents an average ± standard deviation of at least 3 identically and independently prepared samples. PTX/PLGA NPs were significantly larger than PLGA NPs (ANOVA, Tukey test means comparison, p<0.05). Other NPs were not significantly different from each other in size.
