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. Author manuscript; available in PMC: 2013 Sep 19.
Published in final edited form as: Bioconjug Chem. 2012 Aug 10;23(9):1902–1908. doi: 10.1021/bc300273m

Scheme 3.

Scheme 3

18F–labeling of Cys–RLuc8 11 using 18F–4a

a Reagents and conditions: (a) TEV protease (100 μg of protein/10 units of enzyme), 30 °C, 6 h, (b) 18F–4, 37 °C, 30 min, 12 ± 0.7% (decay–corrected to end of synthesis, isolated yield).