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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Anesthesiology. 2012 Oct;117(4):765–771. doi: 10.1097/ALN.0b013e31826a0d93

Figure 2.

Figure 2

Volatile anesthetics’ effect on glycine responses in homomeric α1 wild-type, α1(M287L) and α1(Q266I) expressed in Xenopus oocytes. Isoflurane (0.3 mM) and chloroform (1 mM) potentiation of glycine responses (with a concentration that induced a current that is 5% of the maximal current, effective concentration 5, or EC5) in A) α1 wild-type (n= 6) and α1(M287L) (n= 5), and B) α1 wild-type (n= 4) and α1(Q266I) (n= 4). Values are means ± S.E.M.; *p< 0.01 versus corresponding wild-type, Student’s t-test analysis.