Table 3.
Correlation of methylation status of RB gene with clinicopathological data of gastric carcinoma patients.
| n | Methylated (n) | Unmethylated (n) | χ 2 | P | |
|---|---|---|---|---|---|
| EBV infection | |||||
| EBVaGC | 30 | 24 | 6 | 6.490 | 0.011 |
| EBVnGC | 38 | 19 | 19 | ||
| Age (yr) | |||||
| <50 | 37 | 22 | 15 | 0.498 | 0.481 |
| ≥50 | 31 | 21 | 10 | ||
| Gender | |||||
| Male | 58 | 36 | 22 | — | 0.835 |
| Female | 10 | 7 | 3 | ||
| Pathologic grade | |||||
| Poorly differentiated | 60 | 40 | 20 | — | 0.216 |
| Well-moderately differentiated | 8 | 3 | 5 | ||
| Location | |||||
| Gastric cardia | 14 | 10 | 4 | 3.172 | 0.205 |
| Gastric body | 28 | 20 | 8 | ||
| Antrum | 26 | 13 | 13 | ||
| Depth of invasion | |||||
| Invasion to serosa and invasion through serosa | 46 | 33 | 13 | 4.423 | 0.036 |
| Not invading serosa | 22 | 10 | 12 | ||
| Lymph node metastasis | |||||
| Positive | 38 | 29 | 9 | 6.339 | 0.012 |
| Negative | 30 | 14 | 16 |