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. 2012 Jun 6;3(9):674–681. doi: 10.1021/cn300033k

Figure 7.

Figure 7

Preventive effects of Congo red against Wt-Aβ42 or E22P-Aβ42-induced neurotoxicity and intracellular ROS accumulation. (A, B) In MTT test, cultures were treated with Congo red and (A) Wt-Aβ42 (20 μM) or (B) E22P-Aβ42 (5 μM) for 48 h. (C, D) In DCF assay, cultures were incubated with Congo red and (C) Wt-Aβ42 (20 μM) or (D) E22P-Aβ42 (5 μM) for 24 h. The intrinsic fluorescence of Congo red was subtracted: (∗∗) P < 0.01, (∗∗∗) P < 0.001 vs vehicle, (#) P < 0.05, (###) P < 0.001.