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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Curr Protoc Chem Biol. 2012 Jun 1;4(2):110236. doi: 10.1002/9780470559277.ch110236

Figure 5. ISH of neural crest progenitor marker (crestin) in 24 hpf embryos following chemical treatment.

Figure 5

DMSO (a) is used as a control for crestin expression. Treatment with NSC210627 (b) completely abrogated crestin levels. Based on structural similarities the authors tested Leflunomide (c) that was not found in the original chemical library, but displays robust reduction in crestin expression. (Adapted from White et al. 2011)