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. 2012 Jun 18;80(3):765–778. doi: 10.3797/scipharm.1201-01

Tab. 2.

The transdermal permeation parameters of progesterone obtained after occlusive and non-occlusive application of various formulations.

Formulation Occlusive application Open application

Flux (μg cm−2 h−1) Lag time (h) Flux (μg cm−2 h−1) Lag time (h)
EFME 2.69 (0.24) 3.22 (0.34) 2.36 (0.08) 3.41 (0.64)
20% EME 6.20 (0.68) 1.47 (0.64) 4.48 (1.44) 1.50 (0.14)
40% EME 9.83 (2.77) 0.91 (0.41) 7.25 (2.01) 0.28 (0.22)
ETW 2.22 (0.28) 1.88 (0.31) 1.75 (0.25) 0.29 (0.09)
PGW 1.09 (0.18) 2.45 (0.07) 1.34 (0.33) 3.62 (0.75)

Values between brackets are SEM, n = 3.