Figure 5.

IBP regulates sensitivity to cisplatin in MCF-7 cells. (A) IBP expression was analyzed by Western blot in stable IBP-over-expressing MCF-7 cells and IBP-knockdown MCF-7 cells. C1/MCF-7 and MCF-7/RNAi-cont. cells were respective control cells. (B) Cells were treated with increasing cisplatin concentrations, and their proliferation rates were measured with a CCK-8 assay. (C) Cisplatin IC50 values were determined by CCK cell survival assays. In the columns, the mean was derived from at least three independent experiments. A statistical analysis was performed using Student’s t test. *, p < 0.05, significant