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. 2012 Jun 15;13:42. doi: 10.1186/1471-2369-13-42

Table 1.

Baseline characteristics of 16,010 NHANES III (1988–1994) participants stratified by eGFRMDRDand eGFRCKD-EPI

EGFRMDRD
≥120
90-119
60-89
30-59
<30
(No. of participants)a
(2,729)
(6,604)
(5,606)
(1,015)
(56)
EGFRCKD-EPI ≥120 90-119 ≥120 90-119 60-89 90-119 60-89 30-59 60-89 30-59 <30 <30
Number of participants a (%) b
2,416
312 d
1,473
4,969
162
1,870
3,664
72
120
883
12
55 e
(88.3)
(11.7)
(20.2)
(78.4)
(1.4)
(42.9)
(56.6)
(0.5)
(19.4)
(79.5)
(1.1)
(99.5)
Characteristicc
 
 
 
 
 
 
 
 
 
 
 
 
Serum Creatinine (mg/dl)
0.64
0.59
0.76
0.79
0.70
0.87
0.94
1.07
1.07
1.26
1.97
2.76
(0.004)
(0.01)
(0.003)
(0.002)
(0.01)
(0.004)
(0.004)
(0.03)
(0.02)
(0.02)
(0.11)
(0.20)
EGFRMDRD (ml/min/1.73 m2)
138
131
112
100
98
85
74
61
58
49
31
23
(0.63)
(0.72)
(0.17)
(0.18)
(0.28)
(0.09)
(0.13)
(0.09)
(0.13)
(0.27)
(0.32)
(0.88)
EGFRCKD-EPI (ml/min/1.73 m2)
133
112
124
109
87
96
79
59
63
50
29
22
(0.36)
(0.51)
(0.14)
(0.12)
(0.27)
(0.18)
(0.20)
(0.13)
(0.20)
(0.30)
(0.24)
(0.92)
Age (years)
26 (0.2)
53 (0.8)
28 (0.3)
39 (0.2)
79 (0.5)
40 (0.5)
59 (0.6)
83 (1.0)
56 (1.11)
72 (0.74)
81 (2.12)
72 (1.75)
Age < 65 years, N (%) a b
2,415
247
1,473
4,614
0
1,754
1,717
0
100
115
0
12
(99.9)
(85.8)
(100)
(96.4)
 
(95.8)
(61.3)
 
(83.8)
(18.0)
 
(16.9)
Male (%)
40
55
44
53
56
46
49
60
24
40
72
35
Race/Ethnicity (%)
 
 
 
 
 
 
 
 
 
 
 
 
Non-Hispanic White
52
67
65
74
85
86
86
86
90
86
90
73
Non-Hispanic Black
25
9
19
11
7
4
7
13
1
8
9
18
Mexican American
13
10
8
6
2
4
2
1
2
1
1
2
Other
11
13
9
10
7
6
6
1
6
5
0
8
Ever or Current Smoker (%)
45
68
46
56
47
51
54
43
57
55
84
56
Diabetes (%)
3
13
<1
3
11
3
8
6
14
15
27
26
Prior CVD (%)
<1
<1
<1
3
16
3
10
22
13
26
73
35
Body Mass Index (kg/m2)
25
27
25
26
25
26
27
25
29
28
25
26
(0.23)
(0.75)
(0.20)
(0.14)
(0.26)
(0.20)
(0.15)
(0.45)
(0.68)
(0.24)
(1.02)
(1.18)
Systolic Blood Pressure, mm Hg
112
130
112
119
145
118
131
143
130
143
150
145
(0.46)
(1.90)
(0.34)
(0.31)
(1.86)
(0.45)
(0.59)
(1.99)
(2.22)
(1.03)
(6.01)
(3.66)
Diastolic Blood Pressure, mm Hg
68
78
69
74
73
75
76
72
76
75
71
73
(0.41)
(0.95)
(0.35)
(0.28)
(1.05)
(0.32)
(0.25)
(1.14)
(0.85)
(0.49)
(2.11)
(2.98)
Antihypertensive medication use (%)
4
26
2
10
32
10
27
44
36
60
75
74
Total Cholesterol (mg/dl)
183
217
181
198
208
204
217
213
230
232
209
230
(1.69)
(4.92)
(1.68)
(1.14)
(3.82)
(1.57)
(1.21)
(5.49)
(4.65)
(2.81)
(10.31)
(14.24)
CRP (mg/dl; %)
 
 
 
 
 
 
 
 
 
 
 
 
<0.22
73
58
80
75
71
76
67
62
64
52
29
42
0.22-0.99
19
29
14
19
22
19
25
28
23
32
12
40
≥1.00
9
13
6
6
7
5
8
10
13
16
59
18
ACR (mg/g; %)
 
 
 
 
 
 
 
 
 
 
 
 
<30
93
84
93
94
74
95
89
78
83
70
9
34
30-300
6
11
7
5
25
5
10
18
15
23
68
20
≥300 <1 5 <1 <1 17 1 1 4 3 7 23 46

Abbreviations: CVD, Cardiovascular Disease; eGFR, estimated glomerular filtration rate; MDRD, Modification of Diet in Renal Disease Study; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; CRP, C-reactive protein; ACR, albumin-to-creatinine ratio.

Note: Conversion factors for units: low- and high-density lipoprotein cholesterol in mg/dL to mmol/L, ×0.02586; triglycerides in mg/dL to mmol/L, ×0.01129; creatinine in mg/dL to μmol/L, ×88.4; eGFR in mL/min/1.73 m2 to mL/s/1.73 m2, ×0.01667; albumin-creatinine ratio in mg/g to mg/mmol, divide by 8.84.

a Participant numbers are unweighted N.

b Percent represents the population percent representative of the non-institutionalized US population; total may not equal 100% due to rounding.

c Values presented are population % for categorical variables and mean (linearized standard error) for continuous variables.

d One 86 year old Mexican-American female with serum creatinine = 0.488 mg/dL had eGFRMDRD = 120 ml/min/1.73 m2 and eGFRCKD-EPI 89 ml/min/1.73 m2 (data not shown).

e One 64 year old Mexican-American female with serum creatinine = 1.736 had eGFRMDRD = 29.5 ml/min/1.73 m2 and eGFRCKD-EPI = 30.6 ml/min/1.73 m2 (data not shown).