Table 3.
Univariate and multivariate association between baseline factors and clinical, echocardiographic and biochemical CRT response
| |
Univariate analysis |
Multivariate analysis (MODEL 1) |
Multivariate analysis (MODEL 2) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline variable | Clinical response | LV remodelling | BNP response | Clinical response | LV remodelling | BNP response | Clinical response | LV remodelling | BNP response |
| ICM/NICM |
0.02 |
0.008 |
0.04 |
0.04 |
0.01 |
Ns |
0.046 |
0.02 |
ns |
| QLV |
<0.00001 |
<0.00001 |
0.0001 |
<0.00001 |
<0.00001 |
0.0001 |
- |
- |
- |
| QLV ratio |
<0.00001 |
<0.00001 |
0.001 |
- |
- |
- |
0.0004 |
<0.00001 |
0.01 |
| QRSd |
0.0005 |
0.002 |
0.003 |
ns |
ns |
Ns |
0.04 |
ns |
0.04 |
| LVESD |
0.01 |
0.0006 |
0.12 |
0.009 |
0.0002 |
Ns |
0.01 |
0.0003 |
ns |
| LVEDD | 0.03 | 0.0007 | 0.19 | - | - | - | - | - | - |
The figures are p-values for linear regression between baseline variables and CRT response rates analyzed in two multivariate models that included either QLV (Model 1) or QLV ratio (Model 2). ICM – ischemic cardiomyopathy; NICM – non-ischemic cardiomyopathy. Other abbreviations as in Table 1.